Living and
nonliving and their main features, differences between plants and
animals – plant and animal cell structures, cell inclusions and cell
divisions – mitosis and meiosis.
A brief study of the leading sub divisions of the
plant kinds thallopytes, brophytes, gymnosperms and angiosperms with
examples. Structure, physiology and life history of bacteria and
yeast.
General morphology of root, stem, leaf, flower and
fruit – Different kinds of fissues – anatomical structure of a root
stem and leaf. Very brief account of pillination, fertilization,
fruit and seed formation. Fruit and seed dispersal.
Taxonomy :
A systematic study of the following families : Announaceae,
solanceae, liliaceae, Umbelliferae
Plant
Physicology:
A brief study of (i)
Transpiration
(ii)
Photosynthesis
and (iii)
Respiration.
The Animal kingdom, outline classification with salient
features and examples of each phylum. The structure life history and
physiology of Amoeba paramecium, cockroach & Mosquito.
Classification of Choroata, comparative anatomy of the vertebrate
series of animals with special reference to cardiovascular and nervous
system. Principles of the hgistology of animal fissues.
Parasitology introduction to the more important
protozoan and helmitnth parasites in man and domesticated animals.
Outline of the life history of plasmodium, Trypanasoma and round worm.
PRACTICALS :

Care
anduse of the Microscope

Technical description of plants belonging to the Angiosperms
families prescribed in the syllabus and referring them to their
respective families.

Microscopic study of different tissues and the primary anatomical
structure of a root, stem and leaf.

Microscopic and macroscopic examination and identification of the
types prescribed in the syllabus

Preparation of herbarium sheets.

Experiments in Zoology based on Theory.
T. 1.1 B MATHEMATICS
ALGEBRA :
Arithmetic Progression – Geometric Progression – Permutations and
combinations – Binomical theorem – Partial fractions Matrices –
Determinats – Applications of determinates to solve simultaneous
equations (Cramer’s rule)
TRIGONOMETRY
:
Trigonometric ratios and the relations between them. Sin (A+B), Cos (A+B)
Tan (A+B) formulae only. Trigonometric ratios of multiple angles
Heights and distances (simple problems thereon)
COORDINATE GEOMETRY :
Distance between two pointsArea of a triangle Coordinates of a point
dividing a given segment in a given ratio – locus equations to a
straight line in different form – Angle between straing lines – point
of intersection.
Differential Calculus :
Continuity and limit : Differentiation, derivability and derivative, R.H. derivatives and L.H. derivatives, Differentiation General
theorems of derivation. Derivatives of trigonometric functions
(excluding inverse trigonometric and hyperbolic functions) Logarithmic
differentiation. Partial differentiation maxima and minima
(elementary)
Integral
Calculus :
Integration as inverse process of differentiation definaite integrate
integration by substitution, integration by parts integration of
algebraic function of ex Evaluation of area in simple cases.
Differential equations
:
Formation of a differential equation, order and degree, derivation of
a differential equation. Introduction to Laplace transforms and their
use.
T1.2 PHARMACEUTICAL
CHEMISTRY1 (INOGANIC)
A review
of electronic structure of atom and periodic classification and group
properties of elements
An
outline of methods of preparation and test for purity (including
limits test) of the following classes of inorganic compounds included
in the pharmacopoeia of India. The discussion of assays shall be
excluded.

Acids
and Bases, Buffers and Pharmaceutical aids, antioxidants, water.

Gastro
– Intestinal agents , acidifying agents, antacids, protectives and
adsorbents. Saline cathartcs.

Major
intra and extra cellular electrolytes. Major physiologicalions
Eletrolytes used for replacement therapy. Physiological acid – base
balance. Electrolytes used in acid base therapy. Electrolytic
combination therapy.

Essential and trace elements. Transition elements and their
compounds. Iron and Haematinics. Mineral supplements.

Inorganic pharmaceuticals used for systemic effects. Drugs used
primarily for cationic components. Drugs used primarily for anionic
components.

Topical agents : Oxygen therapy. Antimicrobiasl and Astringents.

Gases
and vapours. Oxygen therapy. Anaesthetic gases. Respiratory
stimulants.

Dental
products. Anticarries agents and dentifrices.

Complexation and chelation.

Radio
pharmaceuticals. Nuclear decomposition. Biological application of
radio active drugs. Radioopaques.

Miscellaneous inorganic pharmaceutical agents.
Sclerosing agents Cathartics and enemas. Eperctorants and emetics.
Poisons and antidotes. Sedative.
P1.2
PRACTICALS :
1.
Systematic qualitative
analysis of inorganic compounds containing up to 4 radicals.
2.
Preparation of
inorganic pharmaceutical compounds.
3.
Limit tests and tests
for impurities
4.
Assay of inorganic
pharmaceuticals.
Text
Books
:

Roger’s Inorganic Pharmaceutical Chemistry

Inorganic Medical and pharmaceutical Chemistry – by Block Roche,
Soine and Wilson.

Modern
Inorganic pharmaceutical Chemistry by Discher.

Text
book of pharmaceutical chemistry by bentely and driver revised by
L.M. Atherden.

Indian
pharmacopoeia.
T1.3 PHARMACEUTICAL CHEMISTRY II (ORGANICI)
The subject of Organic Chemistry will be treated in its
modern
perspective keeping for the sake of convenience of the
usual
classification of Organic compounds but laying emphasis
on
the following aspects:
Structure and properties: Energy of activation,
Transition state;
Freeradical substitution; cycloalkanes; Nucleophilic
aliphatic substitution, carbocations; Elimination; Electrophilic and
Freeradical
addition; Conjugation and Resonance; Nucleophilic
addition and Nucleophilic acyl substitution. Chemistry
of aliphatic
compounds, including preparation and reactions of alkenes,
alkynes, alkylhalides, alcohols, ethers, aldehydes, ketones,
carboxylic acids and esters.
P1.3 PRACTICALS:
1.
Organic
Chemistry Laboratory Techniques.
(a)
Filtration Techniques.
(b)
Determination of Boiling point & Melting point
(c)
Crystallization Techniques.
2.
Experiments in simple qualitative analysis including
prepara
tion of derivatives. (Monofunctional and water insoluble com
pounds should be given.)
3.
Preparation of simple organic compounds illustrating
different
techniques.
TEXT  BOOK:
1.
R.T.Morrison and R.N. Boyd. 'Organic Chemistry'. Allyn
and
Bacon, In., Boston.
2.
I.L Finar, 'Organic Chemistry'. Vol. 1, the English
Language
Book Society, London.
3.
B.S. Fumiss, A.J. Hannaford, V. Rogers, P.W.G. Smith
and
A.M. Tatchell, Vogel's Text Book of Practical Organic
Chemis
try (Including qualitative organic analysis). The
English Language
Book Society.
4.
Study guide to accompany the T.B. of organic chemistry
by
Morrison and Boyd  Morrison & Boyd.5.
Problems and their solution in Organic Chemistry  I.L Finar.
T
1.4 PHYSICAL PHARMACY 1
Intermolecular forces and States of matter; Binding
forces between molecules, the states of matter, the Gaseous state,
the
liquid state, solids and the Crystalline state, Phase
equilibria and the phase rule.
Thermodynamics: The first law of thermodynamics,
Thermochemistry. The second law of thermodynamics. The third law
of thermodynamics Free energy functions and
applications.
Some physical properties of Drug Molecules : Dielectric
constant
Induced polarization, Dipole moment, Refractive Index
and Molar Refraction, Optical Rotation, Optical
Rotatory Dispersion.
Solutions : Concentration expressions, solutions of
nonelectrolytes, ideal and real solutions, colligative properties,
molecular
weight determinations.
Solutions of Electrolytes : Properties of solutions of
electrolytes,
The Arrhenius theory of electrolytic dissociation, The
modern theory of strong electrolytes and other
coefficients for
expressing colligative properties.
Ionic equilibria : Modern theories of acids, bases and
salts,
Sorensen's P ^{H} scale, Species concentration
as a function of
P^{H}, Calculation of P^{H}. Graphical
solution of P^{H} problems, acidity
constants.
Buffers and Buffered Isotonic Systems; The Buffer
Equation,
Buffer capacity, Buffers in pharmaceutical and
Biological systems,
Buffered isotonic solutions, methods of adjusting tonicity
and P^{H}.
lectromotive Force and Oxidation  Reduction systems:
Electrochemical
cells, Electrometric determination of P^{H} and redox.
Viscosity : Viscosity, Poisseulli's formula for
liquids. Experimental
determination of viscosity, Ostwald viscometer. Comparison
of viscosities.
P1.4 Practicals :
Experiments based on theory
Text Books:
1.
Physical Pharmacy by Alfred Martin
2.
Bentley's Text book of Pharmaceutics by E.A. Rawlins
3. Remington's pharmaceutical Sciences
T
1.5 PHARMACEUTICS 1
1.
History of Pharmacy :
Pharmacy Profession, Pharmacy as a
career, Evolution of Pharmacy 
Pharmacopoeia of India and
other countries, B.P., B.P.C., U.S.P.
Metrology
: Systems of Weights and Measures  Metric and
Imperial systems  Percentage calculations and
adjustment of products  Interconversions  Use of alligation method
in
calculations  Isotonic solutions and proof spirits 
Weighing Selection
and care of Weights and balances.
2. Packaging and Labelling of Pharmaceuticals : Desirable features
of a container  Types of containers  Study of glass and
plastics as materials for
containers and rubber as a material for closures  their merits
and demerits  Labelling requirements.
3. Introduction to Dosage Forms  Classification 
Types with
examples, Definitions and essential characteristics of
different
dosage forms  Formulation and its purpose formulation
Additives : Solvents, Vehicles for Liquids,
Antioxidants, Preservatives,
Colouring agents, Sweetening and flavouring
agents in Liquid dosage forms.
4. Liquid oral dosage forms : Definitions, general
formulation,
methods of preparation, uses of official and other
products in
common usage of the following :
Solutions, Aromatic Waters, Spirits, Syrups, Elixirs,
Dry Syrups,
Mixtures.
5. Monophasic Liquids for external
and other uses : Definitions,
general formulation, methods of preparation, uses of official
and other products in common usage of the following:
Lotions, Liniments, throat paints, gargles,
mouthwashes,
glycerins, collodions, Ear drops, Nasal drops and
Sprays,
Douches.
6. Biphasic liquid dosage Forms : Suspensions 
Definitions,
Types, Ideal requirements, Formulation additives, Typical
examples for oral and external use, Methods of preparation.
7. Galenicals : Study of extraction processes 
Maceration
Percolation and their modifications, continuous hot
extraction  Their applications. Principles and methods of preparations
of dry, soft and liquid extracts and tinctures of IP and BP (Latest
editions).
8. Suppositories and Pessaries : Ideal requirements,
different bases, Preparation methods  Typical examples, calculations
involving displacement value  Packaging and
supply.
P1.5 PRACTICALS :
Preparation of atleast 50
Pharmaceutical
products.
TEXT BOOKS :
1.
Bentley's Text book of Pharmaceutics Introduction to
2.
Pharmaceutical Dosage Forms by H.c. Ansel
Cooper and
3.
Gunn's  Dispensing for Pharmaceutical students
4.
American Pharmacy by Sprowls
5.
IP. 3rd Edition
6.
Remington's Pharmaceutical Sciences.
7.
General Pharmacy and Professional Pharmacy by M.L.
Schroff
T 1.6 PHARMACEUTICAL
ANALYSIS 1
1.
Balances  different types and weighing. Types of
analysis,
obtaining sample, measurement of sample and types of pi
pettes. Computation of Analytical Results : Significant
num
bers, sources of errors and their rectification,
statistical treat
ment of the data and rejection of data.
2. Ionic equations of solutions; stoichiometric and
Analytical prob
lems: Determination of Normality, percentage purity,
Molarity,
Molality and their interconversions.
3. Principles of volumetric and Gravimetric Analysis :
Standardisation; use of primary and secondary
standards. Acid
base concept, common ion effect and solubility product,
P^{H
}
and Buffers.
4. General Principles and theory of acidimetry,
alkalimetry, Oxi
dation  reduction methods, precipitation methods. An
account
of the indicators used in these titrajtions.
Diazotisation titra
tions.
5. Gravimetric methods /: Typical methods involving
precipita
tion, coagulation, incineration oj^digestion
procedures.
6. Complexometric Titrationr rTheory, types and
application in
pharmaceutical analysis. Masking and damasking and its
ap
plication.
7.
Nonaqueous Titrations Theory, types and application in
phar
maceutical analysis.
8. Determination
of Moisture content and Alcohol content, Theory
and methods involved.
9. Polarimetry : Theory, Instrumentation and applications.
Re
fractometry, Theory, instrumentation (Abbes, Pulfrisch
and
Immersion)
and applications.
10. Principles of gas analysis.
P1.6
PRACTICALS:
Experiments based on theory.
TEXT BOOKS:
1.
Quantitative Inorganic Analysis by A.I. Vogel
2. Bentley and Driver  Text book of Pharmaceutical
Chemistry
3.
Practical Pharmaceutical Chemistry  A.M. Backett and
J.B.
Stenlake
4.
I.P
5.
Quantitative Pharmaceutical Chemistry by Chatten
T 1.7 COMPUTER APPLICATIONS AND STATISTICALMETHODS
Introduction to computers development, computer types,
characteristics,
anatomy  input and out put devices and other
components 
computer codes and arithmetic, flow chart, algorithm, languages
Basic Language : Basic Programme structure, constants,
variables, expressions, let, rem, stop and end
statements, input / output statements, control statements, subscripted
variables, functions and subprogrammes,
additional statements,
simple programme writing related to statistics.
Introduction to DOS environment DOS usage.
Fundamentals of Basic language : Basic programmes,
structure,
loading and Unloading, Basic interpreter, Basic alphabet,
constants, variables, operators, Expressions, hirarchy of operations.
Branching and looping :
IF THEN, ELSEGO TO, ON GO TO,
GO SUB, ON GO SUB, WHILEWEND, FOR TO NEXT.
Arrays: Subscribed variable,
single and multiple dimensions
Graphs and sound : LINE, CIRCLE, DRAW, PSET,POINT,
PAINT, PUT, GET, SOUND, PLAY etc.,
File handling: Data files, random data files, file
creation, reading
random files.
Introduction to dBASE III PLUS, getting started,
viewing and
editing data, modifying structure and file utilities,
managing
data base, printing reports and labels, memory
variables and
funtions and command files.
Programmeing with dBASE III PLUS, mathematical commands
and other functions multiple data base files, designing
custom screens, error conditions and program debugging
aids, advanced features of the dBASE IIIPLUS,
applications generator, payroll problem, development of
inventorycontrol
package, protection and networking. Application of Computers in
Pharmacy.
2. Introduction to statistics, chance variations,
collection, classification,
graphical and pictorial representation of data, Measures of central
tendency and dispersion, precision and Accuracy  Measures of error.
Probability, Normal and binomial distributions,
sampling distributions
 standard error and Fiducial limits, t  test and chi square
test of significance  Principle involved and applications.
Correlation coefficient and Regression analysis 
Method of
least squares.
P1.7 PRACTICALS:
Computer usage
Simple programme writing related to statistics.
Statistical Methods : Solving problems based on theory.
TEXT BOOKS:
1.
Remington's Pharmaceutical Sciences.
2. Basic Computer Programming by Er. V.K. Jain
3. Biostatistics by Alwin L. Lewis
4. Computers
and common sense  N. Hunt and J. Shelley.
