non-living and their main features, differences between plants and
animals – plant and animal cell structures, cell inclusions and cell
divisions – mitosis and meiosis.
A brief study of the leading sub divisions of the
plant kinds thallopytes, brophytes, gymnosperms and angiosperms with
examples. Structure, physiology and life history of bacteria and
General morphology of root, stem, leaf, flower and
fruit – Different kinds of fissues – anatomical structure of a root
stem and leaf. Very brief account of pillination, fertilization,
fruit and seed formation. Fruit and seed dispersal.
A systematic study of the following families : Announaceae,
solanceae, liliaceae, Umbelliferae
A brief study of (i)
The Animal kingdom, outline classification with salient
features and examples of each phylum. The structure life history and
physiology of Amoeba paramecium, cockroach & Mosquito.
Classification of Choroata, comparative anatomy of the vertebrate
series of animals with special reference to cardiovascular and nervous
system. Principles of the hgistology of animal fissues.
Parasitology introduction to the more important
protozoan and helmitnth parasites in man and domesticated animals.
Outline of the life history of plasmodium, Trypanasoma and round worm.
anduse of the Microscope
Technical description of plants belonging to the Angiosperms
families prescribed in the syllabus and referring them to their
Microscopic study of different tissues and the primary anatomical
structure of a root, stem and leaf.
Microscopic and macroscopic examination and identification of the
types prescribed in the syllabus
Preparation of herbarium sheets.
Experiments in Zoology based on Theory.
T. 1.1 B MATHEMATICS
Arithmetic Progression – Geometric Progression – Permutations and
combinations – Binomical theorem – Partial fractions Matrices –
Determinats – Applications of determinates to solve simultaneous
equations (Cramer’s rule)
Trigonometric ratios and the relations between them. Sin (A+B), Cos (A+B)
Tan (A+B) formulae only. Trigonometric ratios of multiple angles-
Heights and distances (simple problems thereon)
CO-ORDINATE GEOMETRY :-
Distance between two points-Area of a triangle Co-ordinates of a point
dividing a given segment in a given ratio – locus equations to a
straight line in different form – Angle between straing lines – point
Differential Calculus :
Continuity and limit : Differentiation, derivability and derivative, R.H. derivatives and L.H. derivatives, Differentiation General
theorems of derivation. Derivatives of trigonometric functions
(excluding inverse trigonometric and hyperbolic functions) Logarithmic
differentiation. Partial differentiation maxima and minima
Integration as inverse process of differentiation definaite integrate
integration by substitution, integration by parts integration of
algebraic function of ex Evaluation of area in simple cases.
Formation of a differential equation, order and degree, derivation of
a differential equation. Introduction to Laplace transforms and their
of electronic structure of atom and periodic classification and group
properties of elements
outline of methods of preparation and test for purity (including
limits test) of the following classes of inorganic compounds included
in the pharmacopoeia of India. The discussion of assays shall be
and Bases, Buffers and Pharmaceutical aids, antioxidants, water.
– Intestinal agents , acidifying agents, antacids, protectives and
adsorbents. Saline cathartcs.
intra and extra cellular electrolytes. Major physiologicalions
Eletrolytes used for replacement therapy. Physiological acid – base
balance. Electrolytes used in acid base therapy. Electrolytic
Essential and trace elements. Transition elements and their
compounds. Iron and Haematinics. Mineral supplements.
Inorganic pharmaceuticals used for systemic effects. Drugs used
primarily for cationic components. Drugs used primarily for anionic
Topical agents : Oxygen therapy. Antimicrobiasl and Astringents.
and vapours. Oxygen therapy. Anaesthetic gases. Respiratory
products. Anticarries agents and dentifrices.
Complexation and chelation.
pharmaceuticals. Nuclear decomposition. Biological application of
radio active drugs. Radio-opaques.
Miscellaneous inorganic pharmaceutical agents.
Sclerosing agents Cathartics and enemas. Eperctorants and emetics.
Poisons and antidotes. Sedative.
analysis of inorganic compounds containing up to 4 radicals.
inorganic pharmaceutical compounds.
Limit tests and tests
Assay of inorganic
Roger’s Inorganic Pharmaceutical Chemistry
Inorganic Medical and pharmaceutical Chemistry – by Block Roche,
Soine and Wilson.
Inorganic pharmaceutical Chemistry by Discher.
book of pharmaceutical chemistry by bentely and driver revised by
T1.3 PHARMACEUTICAL CHEMISTRY -II (ORGANIC-I)
The subject of Organic Chemistry will be treated in its
perspective keeping for the sake of convenience of the
classification of Organic compounds but laying emphasis
the following aspects:
Structure and properties: Energy of activation,
Free-radical substitution; cyclo-alkanes; Nucleophilic
aliphatic substitution, carbocations; Elimination; Electrophilic and
addition; Conjugation and Resonance; Nucleophilic
addition and Nucleophilic acyl substitution. Chemistry
compounds, including preparation and reactions of alk-enes,
alkynes, alkylhalides, alcohols, ethers, aldehydes, ke-tones,
carboxylic acids and esters.
Chemistry Laboratory Techniques.
Determination of Boiling point & Melting point
Experiments in simple qualitative analysis including
tion of derivatives. (Monofunctional and water insoluble com
pounds should be given.)
Preparation of simple organic compounds illustrating
TEXT - BOOK:
R.T.Morrison and R.N. Boyd. 'Organic Chemistry'. Allyn
Bacon, In., Boston.
I.L Finar, 'Organic Chemistry'. Vol. 1, the English
Book Society, London.
B.S. Fumiss, A.J. Hannaford, V. Rogers, P.W.G. Smith
A.M. Tatchell, Vogel's Text Book of Practical Organic
try (Including qualitative organic analysis). The
Study guide to accompany the T.B. of organic chemistry
Morrison and Boyd - Morrison & Boyd.5.
Problems and their solution in Organic Chemistry - I.L Finar.
1.4 PHYSICAL PHARMACY -1
Intermolecular forces and States of matter; Binding
forces between molecules, the states of matter, the Gaseous state,
liquid state, solids and the Crystalline state, Phase
equilibria and the phase rule.
Thermodynamics: The first law of thermodynamics,
Thermo-chemistry. The second law of thermodynamics. The third law
of thermodynamics Free energy functions and
Some physical properties of Drug Molecules : Dielectric
Induced polarization, Dipole moment, Refractive Index
and Molar Refraction, Optical Rotation, Optical
Solutions : Concentration expressions, solutions of
nonelec-trolytes, ideal and real solutions, colligative properties,
Solutions of Electrolytes : Properties of solutions of
The Arrhenius theory of electrolytic dissociation, The
modern theory of strong electrolytes and other
expressing colligative properties.
Ionic equilibria : Modern theories of acids, bases and
Sorensen's P H scale, Species concentration
as a function of
PH, Calculation of PH. Graphical
solution of PH problems, acidity
Buffers and Buffered Isotonic Systems; The Buffer
Buffer capacity, Buffers in pharmaceutical and
Buffered isotonic solutions, methods of adjusting tonic-ity
lectromotive Force and Oxidation - Reduction systems:
cells, Electrometric determination of PH and re-dox.
Viscosity : Viscosity, Poisseulli's formula for
determination of viscosity, Ostwald viscometer. Comparison
P1.4 Practicals :
Experiments based on theory
Physical Pharmacy by Alfred Martin
Bentley's Text book of Pharmaceutics by E.A. Rawlins
3. Remington's pharmaceutical Sciences
1.5 PHARMACEUTICS -1
History of Pharmacy :
Pharmacy Profession, Pharmacy as a
career, Evolution of Pharmacy -
Pharmacopoeia of India and
other countries, B.P., B.P.C., U.S.P.
: Systems of Weights and Measures - Metric and
Imperial systems - Percentage calculations and
adjustment of products - Interconversions - Use of alligation method
calculations - Isotonic solutions and proof spirits -
and care of Weights and balances.
2. Packaging and Labelling of Pharmaceuticals : Desirable features
of a container - Types of containers - Study of glass and
plastics as materials for
containers and rubber as a material for closures - their merits
and demerits - Labelling requirements.
3. Introduction to Dosage Forms - Classification -
examples, Definitions and essential characteristics of
dosage forms - Formulation and its purpose formulation
Additives : Solvents, Vehicles for Liquids,
Colouring agents, Sweetening and flavouring
agents in Liquid dosage forms.
4. Liquid oral dosage forms : Definitions, general
methods of preparation, uses of official and other
common usage of the following :
Solutions, Aromatic Waters, Spirits, Syrups, Elixirs,
5. Monophasic Liquids for external
and other uses : Definitions,
general formulation, methods of preparation, uses of official
and other products in common usage of the following:
Lotions, Liniments, throat paints, gargles,
glycerins, collodions, Ear drops, Nasal drops and
6. Biphasic liquid dosage Forms : Suspensions -
Types, Ideal requirements, Formulation additives, Typical
examples for oral and external use, Methods of preparation.
7. Galenicals : Study of extraction processes -
Percolation and their modifications, continuous hot
extraction - Their applications. Principles and methods of preparations
of dry, soft and liquid extracts and tinctures of IP and BP (Latest
8. Suppositories and Pessaries : Ideal requirements,
different bases, Preparation methods - Typical examples, calculations
involving displacement value - Packaging and
P1.5 PRACTICALS :
Preparation of atleast 50
TEXT BOOKS :
Bentley's Text book of Pharmaceutics Introduction to
Pharmaceutical Dosage Forms by H.c. Ansel
Gunn's - Dispensing for Pharmaceutical students
American Pharmacy by Sprowls
IP. 3rd Edition
Remington's Pharmaceutical Sciences.
General Pharmacy and Professional Pharmacy by M.L.
T 1.6 PHARMACEUTICAL
Balances - different types and weighing. Types of
obtaining sample, measurement of sample and types of pi
pettes. Computation of Analytical Results : Significant
bers, sources of errors and their rectification,
ment of the data and rejection of data.
2. Ionic equations of solutions; stoichiometric and
lems: Determination of Normality, percentage purity,
Molality and their interconversions.
3. Principles of volumetric and Gravimetric Analysis :
Standardisation; use of primary and secondary
base concept, common ion effect and solubility product,
4. General Principles and theory of acidimetry,
dation - reduction methods, precipitation methods. An
of the indicators used in these titrajtions.
5. Gravimetric methods /: Typical methods involving
tion, coagulation, incineration oj^digestion
6. Complexometric Titrationr rTheory, types and
pharmaceutical analysis. Masking and damasking and its
Non-aqueous Titrations Theory, types and application in
of Moisture content and Alcohol content, Theory
and methods involved.
9. Polarimetry : Theory, Instrumentation and applications.
fractometry, Theory, instrumentation (Abbes, Pulfrisch
10. Principles of gas analysis.
Experiments based on theory.
Quantitative Inorganic Analysis by A.I. Vogel
2. Bentley and Driver - Text book of Pharmaceutical
Practical Pharmaceutical Chemistry - A.M. Backett and
Quantitative Pharmaceutical Chemistry by Chatten
T 1.7 COMPUTER APPLICATIONS AND STATISTICALMETHODS
Introduction to computers development, computer types,
anatomy - input and out put devices and other
computer codes and arithmetic, flow chart, algorithm, languages
Basic Language : Basic Programme structure, constants,
variables, expressions, let, rem, stop and end
statements, input / output statements, control statements, subscripted
variables, functions and sub-programmes,
simple programme writing related to statistics.
Introduction to DOS environment DOS usage.
Fundamentals of Basic language : Basic programmes,
loading and Unloading, Basic interpreter, Basic alphabet,
constants, variables, operators, Expressions, hirarchy of operations.
Branching and looping :
IF -THEN, ELSE-GO TO, ON GO TO,
GO SUB, ON GO SUB, WHILE-WEND, FOR TO NEXT.
Arrays: Subscribed variable,
single and multiple dimensions
Graphs and sound : LINE, CIRCLE, DRAW, PSET,POINT,
PAINT, PUT, GET, SOUND, PLAY etc.,
File handling: Data files, random data files, file
Introduction to dBASE III PLUS, getting started,
editing data, modifying structure and file utilities,
data base, printing reports and labels, memory
funtions and command files.
Programmeing with dBASE III PLUS, mathematical commands
and other functions multiple data base files, designing
custom screens, error conditions and program debugging
aids, advanced features of the dBASE IIIPLUS,
applications generator, pay-roll problem, development of
package, protection and networking. Application of Computers in
2. Introduction to statistics, chance variations,
graphical and pictorial representation of data, Measures of central
tendency and dispersion, precision and Accuracy - Measures of error.
Probability, Normal and binomial distributions,
- standard error and Fiducial limits, t - test and chi -square
test of significance - Principle involved and applications.
Correlation coefficient and Regression analysis -
Simple programme writing related to statistics.
Statistical Methods : Solving problems based on theory.
Remington's Pharmaceutical Sciences.
2. Basic Computer Programming by Er. V.K. Jain
3. Biostatistics by Alwin L. Lewis
and common sense - N. Hunt and J. Shelley.